Polygodial

SIGMA/SML0049 - ≥97% (HPLC)

Synonym: (1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-Octahydro-5,5,8a-trimethyl-1,2-naphthalenedicarboxaldehyde

CAS Number: 6754-20-7
Empirical Formula (Hill Notation): C₁₅H₂₂O₂
Molecular Weight: 234.33
Linear Formula: C₁₅H₂₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0049-10MG	10 mg	$215.00 1/EA	Add To Favorites
45-SML0049-50MG	50 mg	$836.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
color	white to beige
form	powder
InChI	1S/C15H22O2/c1-14(2)7-4-8-15(3)12(10-17)11(9-16)5-6-13(14)15/h5,9-10,12-13H,4,6-8H2,1-3H3/t12-,13-,15+/m0/s1
InChI key	AZJUJOFIHHNCSV-KCQAQPDRSA-N
Quality Level	100
SMILES string	O=C[C@@H]1[C@@]2([C@H](C(CCC2)(C)C)CC=C1C=O)C
solubility	DMSO: 20 mg/mL, clear
storage temp.	−20°C

Biochem/physiol Actions:	Polygodial is a selective activator of Transient Receptor Potential Anykrin 1 (TRPA1) channels. Initially painful, polygodial acts as an analgesic by desensitizing sensory neuron. Polygodial also has broad antifungal properties, and is cytotoxic against bacteria and algae.
Biochem/physiol Actions:	Polygodial is a sesquiterpene dialdehyde. It is obtained from the plants Polygonum hydropiper, Warburgia ugandensis, Pseudowintera colorata and Warburgia stuhlmannii. It exhibits antifeedant activity and antimicrobial activity against insects and microbes, respectively. It is responsible for the “hot taste” in peppery spices of traditional Japanese cuisine.
Biochem/physiol Actions:	Polygodial is a TRPA1 activator; antifungal.
Packaging:	10, 50 mg in glass bottle

Risk Statements	52/53
Safety Statements	61
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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