Salsalate
SIGMA/SML0070 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 552-94-3
Empirical Formula (Hill Notation): C14H10O5
Molecular Weight: 258.23
EC Number: 209-027-4
MDL Number: MFCD00020252
Linear Formula: C14H10O5
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to tan |
| form | powder |
| InChI | 1S/C14H10O5/c15-11-7-3-1- |
| InChI key | WVYADZUPLLSGPU-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | OC(=O)c1ccccc1OC(=O)c2ccc |
| solubility | DMSO: ≥15 mg/mL |
| storage temp. | room temp |
| Application: | Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats. |
| Biochem/physiol Actions: | NSAID; Nonacetylated aspirin analog |
| Biochem/physiol Actions: | Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes. |
| Packaging: | 50, 250 mg in glass bottle |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H400 |
| Precautionary statements | P273 - P301 + P312 + P330 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50 |
| Safety Statements | 61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |