WZ811

SIGMA/SML0088 - ≥98% (HPLC)

Synonym: N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine

CAS Number: 55778-02-4
Empirical Formula (Hill Notation): C₁₈H₁₈N₄
Molecular Weight: 290.36
MDL Number: MFCD18086914
Linear Formula: C₁₈H₁₈N₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0088-5MG	5 mg	$97.50 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to tan
form	powder
InChI	1S/C18H18N4/c1-3-11-19-17(5-1)21-13-15-7-9-16(10-8-15)14-22-18-6-2-4-12-20-18/h1-12H,13-14H2,(H,19,21)(H,20,22)
InChI key	KBVFRXIGQQRMEF-UHFFFAOYSA-N
Quality Level	100
SMILES string	C(Nc1ccccn1)c2ccc(CNc3ccccn3)cc2
solubility	DMSO: ≥7 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	WZ811 is a CXCR4 Antagonist
Biochem/physiol Actions:	WZ811 is a potent, specific antagonist of CXCR4 (IC50 = 0.3 nM). WZ811 blocks SDF-1 mediated changes in cellular cAMP levels in U87 glioma cells (IC50 = 1.2 nM) and Matirgel infiltration of MDA-MB-231 cells (IC50 = 5.2 nM).
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H315 - H319 - H335
Precautionary statements	P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	51111800

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