WZ811
SIGMA/SML0088 - ≥98% (HPLC)
Synonym: N1,N4-
CAS Number: 55778-02-4
Empirical Formula (Hill Notation): C18H18N4
Molecular Weight: 290.36
MDL Number: MFCD18086914
Linear Formula: C18H18N4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to tan |
form | powder |
InChI | 1S/C18H18N4/c1-3-11-19-17 |
InChI key | KBVFRXIGQQRMEF-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | C(Nc1ccccn1)c2ccc(CNc3ccc |
solubility | DMSO: ≥7 mg/mL |
storage temp. | 2-8°C |
Biochem/physiol Actions: | WZ811 is a potent, specific antagonist of CXCR4 (IC50 = 0.3 nM). WZ811 blocks SDF-1 mediated changes in cellular cAMP levels in U87 glioma cells (IC50 = 1.2 nM) and Matirgel infiltration of MDA-MB-231 cells (IC50 = 5.2 nM). |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 - H315 - H319 - H335 |
Precautionary statements | P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |