Bikinin
SIGMA/SML0094 - ≥98% (HPLC)
Synonym: 4-
CAS Number: 188011-69-0
Empirical Formula (Hill Notation): C9H9BrN2O3
Molecular Weight: 273.08
MDL Number: MFCD00116442
Linear Formula: C9H9BrN2O3
Product Type: Chemical
application(s) | agriculture |
assay | ≥98% (HPLC) |
color | white to tan |
form | powder |
InChI | 1S/C9H9BrN2O3/c10-6-1-2-7 |
InChI key | XFYYQDHEDOXWGA-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | OC(=O)CCC(=O)Nc1ccc(Br)cn |
solubility | DMSO: ≥5 mg/mL |
storage temp. | 2-8°C |
Application: | Bikinin has been used: • as a glycogen synthase kinase-3 (GSK3) inhibitor in Arabidopsis Col-0 seedlings to test its effect on gene expression • as a component of induction medium and as a GSK3 inhibitor to test its effect on mesophyll cells in Arabidopsis leaf discs or cotyledons • as a brassinosteroid agonist to test its effect on the leaf index of R. trichophyllus terrestrial leaves |
Biochem/physiol Actions: | Bikinin is a strong activator of brassinosteroid (BR) signaling. It is an Arabidopsis GSK-3 Inhibitor, an Arabidopsis SHAGGY-related Kinase Inhibitor, and a GSK-3-like Kinase BIN2 Inhibitor. Bikinin directly inhibits BIN2 (group II GSK3s) by interfering with ATP binding. Bikinin is specific toward a subset of Arabidopsis GSK3 kinases including BIN2 and ASK α, γ, ε, ι, and θ. |
Packaging: | 5, 25 mg in glass bottle |
Hazard Codes | Xn |
Risk Statements | 22-36 |
Safety Statements | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |