Cinnabarinic Acid
SIGMA/SML0096 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 606-59-7
Empirical Formula (Hill Notation): C14H8N2O6
Molecular Weight: 300.22
MDL Number: MFCD18379297
Linear Formula: C14H8N2O6
Product Type: Chemical
assay | ≥98% (HPLC) |
color | red to very dark red |
form | powder |
InChI | 1S/C14H8N2O6/c15-10-6(17) |
InChI key | FSBKJYLVDRVPTK-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NC1=C(C(O)=O)C2=Nc3c(OC2= |
solubility | DMSO: ≥4 mg/mL |
storage condition | desiccated |
storage temp. | 2-8°C |
Application: | Cinnabarinic acid may be used in studies of the functions of components of the kynurenine metabolic pathway. It may be used to study it role as a metabotropic glutamate receptor (mGlu4R-specific) agonist. |
Biochem/physiol Actions: | Caspase Inducer; mGlu4R agonist Cinnabarinic acid (CA) connects between initiation of the kynurenine pathway and immune tolerance that is used to prevent neuroinflammation. |
Biochem/physiol Actions: | Cinnabarinic acid is a kynurenine pathway metabolite of tryptophan, produced by the oxidation of 3-Hydroxyanthranilic acid. Cinnabarinic acid leads to loss of mitochondrial respiration and apoptosis, and has also been shown to be an mGlu4R-specific agonist. |
Features and Benefits: | This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352106 |