Acrivastine
SIGMA/SML0119 - ≥98% (HPLC)
Synonym: (E)
CAS Number: 87848-99-5
Empirical Formula (Hill Notation): C22H24N2O2
Molecular Weight: 348.44
MDL Number: MFCD00869830
Linear Formula: C22H24N2O2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C22H24N2O2/c1-17-7-9-1 |
InChI key | PWACSDKDOHSSQD-IUTFFREVSA |
Quality Level | 100 |
SMILES string | Cc1ccc(cc1)C(=C/CN2CCCC2 |
solubility | DMSO: >2 mg/mL (warmed) |
storage condition | desiccated |
storage temp. | 2-8°C |
Application: | Acrivastine has been used as an antihistamine to investigate the relation between the increased residence time of antihistamine at the histamine H1 receptor (H1R) and the duration of effective target-inhibition by this antagonist. |
Biochem/physiol Actions: | Acrivastine is a second-generation antihistamine, an H1-receptor antagonist. |
Biochem/physiol Actions: | Acrivastine is a second-generation antihistamine. It is a derivative of first-generation compound triprolidine. Acrivastine is effectively used for treating allergic diseases including cholinergic urticaria and histamine-medicated dermatoses. |
Packaging: | 10, 50 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |