BTZO-1

SIGMA/SML0121 - ≥98% (HPLC)

Synonym: 2-Pyridin-2-yl-4H-1,3-benzothiazin-4-one

CAS Number: 99420-15-2
Empirical Formula (Hill Notation): C₁₃H₈N₂OS
Molecular Weight: 240.28
MDL Number: MFCD19690951
Linear Formula: C₁₃H₈N₂OS
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0121-5MG	5 mg	$84.40 1/EA		Add To Favorites
45-SML0121-25MG	25 mg	$328.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to tan
form	powder
InChI	1S/C13H8N2OS/c16-12-9-5-1-2-7-11(9)17-13(15-12)10-6-3-4-8-14-10/h1-8H
InChI key	GBAKVEWPYUIGHN-UHFFFAOYSA-N
originator	Takeda
Quality Level	100
SMILES string	O=C1N=C(Sc2ccccc12)c3ccccn3
solubility	DMSO: ≥7 mg/mL
storage temp.	2-8°C

Application:	BTZO-1 may be used in ARE-mediated gene expression studies.
Biochem/physiol Actions:	BTZO-1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. BTZO-1 binds to the macrophage migration inhibitory factor (MIF) that is required to activate the glutathione S-transferase Ya subunit (GST Ya) gene ARE.
Biochem/physiol Actions:	suppressor of cardiomyocyte apoptosis; ligand of macrophage migration inhibitory factor (MIF)
Features and Benefits:	This compound was developed by Takeda . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	5, 25 mg in glass bottle

Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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