Rasagiline mesylate
SIGMA/SML0124 - ≥98% (HPLC)
Synonym: (1R)
CAS Number: 161735-79-1
Empirical Formula (Hill Notation): C12H13N · CH4O3S
Molecular Weight: 267.34
MDL Number: MFCD08460604
Linear Formula: C12H13N · CH4O3S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to tan |
form | powder |
InChI | 1S/C12H13N.CH4O3S/c1-2-9- |
InChI key | JDBJJCWRXSVHOQ-UTONKHPSSA |
optical activity | [α]/D +15 to +28°, c = 0.6 mg/mL in H2O |
Quality Level | 100 ![]() |
SMILES string | CS(O)(=O)=O.C#CCN[C@@H]1C |
solubility | H2O: ≥20 mg/mL |
storage condition | desiccated |
storage temp. | 2-8°C |
Application: | Rasagiline mesylate has been used: • to test its neuroprotective effects in retinitis pigmentosa (RP) by apoptosis regulator, Bax/Bcl-2 modulation • as monoamine oxidase-B inhibitor in 1-methyl-4-phenyl-1,2,3,6 • as an anti-parkinsonian agent to test its rescue functionality in 6-hydroxydopamine-lesione |
Application: | Rasagiline mesylate may be used in MAO type B-mediated cell signaling studies. |
Biochem/physiol Actions: | Rasagiline mesylate is an effective therapeutic option in early stages of Parkinson′s disease. It improves the motor fluctuations in levodopa-treated patients and may be a useful adjunct to such patients. It has neuroprotective effects and increases the survival of dopaminergic neurons. |
Biochem/physiol Actions: | Rasagiline mesylate is an irreversible inhibitor of monoamine oxidase selective for MAO type B over type A by a factor of fourteen. It has anti-apoptotic and neuroprotectant activity and has been used as a treatment for Parkinson′s disease. |
Features and Benefits: | This compound is featured on the Dopamine and Norepinephrine Metabolism ![]() ![]() ![]() |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |