M30 dihydrochloride
SIGMA/SML0128 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 64821-19-8
Empirical Formula (Hill Notation): C14H14N2O · 2HCl
Molecular Weight: 299.20
MDL Number: MFCD20488063
Linear Formula: C14H14N2O · 2HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | green-yellow |
| form | powder |
| InChI | 1S/C14H14N2O.2ClH/c1-3-9- |
| InChI key | XJNICPXVRPOSSO-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Cl.Cl.CN(CC#C)Cc1ccc(O)c2 |
| solubility | DMSO, heptane and xylene: ≥21 mg/mL |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Application: | M30 dihydrochloride may be used in monamine oxidase-mediated cell signaling studies. |
| Biochem/physiol Actions: | M30 is a site-activated iron chelator and monoamine oxidase (MAO) inhibitor; with neuroprotective and anti-apoptotic activity. It is a multifunctional non-toxic, brain permeable iron chelator possessing a neuroprotective propargylamine moiety and an antioxidant-iron chelator moiety. M30 is a selective irreversible inhibitor of mitochondrial brain monoamine oxidases A and B (MAO-A and -B), providing for improved levels of neurotransmitters. It reduces oxidative damage and shows neuroprotective and neurorestorative effects in various neurodegenerative models of ALS, Alzheimer′s and Parkinson′s diseases, and is being investigated in other diseases where oxidative stress is a problem. |
| Features and Benefits: | This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H318 |
| Precautionary statements | P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310 |
| Hazard Codes | Xn |
| Risk Statements | 22-41 |
| Safety Statements | 26-39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |