ABT-751 hydrochloride

SIGMA/SML0131 - ≥98% (HPLC)

Synonym: N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide hydrochloride

CAS Number: 141450-48-8
Empirical Formula (Hill Notation): C₁₈H₁₇N₃O₄S · HCl
Molecular Weight: 407.87
MDL Number: MFCD19440802
Linear Formula: C₁₈H₁₇N₃O₄S · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0131-5MG	5 mg	$142.00 1/EA	Add To Favorites
45-SML0131-25MG	25 mg	$545.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	pink to purple
form	powder
InChI	1S/C18H17N3O4S.ClH/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13;/h2-12,21-22H,1H3,(H,19,20);1H
InChI key	KWQWWUXRGIIBAS-UHFFFAOYSA-N
originator	Abbott
Quality Level	100
SMILES string	Cl.COc1ccc(cc1)S(=O)(=O)Nc2cccnc2Nc3ccc(O)cc3
solubility	DMSO: ≥15 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	ABT-751 is an orally bioavailable vascular disrupting agent (VDA) with a broad spectrum of antitumor activity. It binds to the colchicine binding site on β-tubulin and inhibits polymerization of microtubules.
Biochem/physiol Actions:	ABT-751, a sulfonamide antimitotic agent, is under clinical trials to treat patients with various malignancies including refractory hematologic malignancies, non-small cell lung cancer (NSCLC), and colon cancer.
Features and Benefits:	This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H315 - H319 - H335
Precautionary statements	P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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