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ABT-751 hydrochloride

SIGMA/SML0131 - ≥98% (HPLC)

Synonym: N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide hydrochloride

CAS Number: 141450-48-8
Empirical Formula (Hill Notation): C18H17N3O4S · HCl
Molecular Weight: 407.87
MDL Number: MFCD19440802
Linear Formula: C18H17N3O4S · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0131-5MG 5 mg
 $156.00
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45-SML0131-25MG 25 mg
 $601.00
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assay ≥98% (HPLC)
color pink to purple
form powder
InChI 1S/C18H17N3O4S.ClH/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13;/h2-12,21-22H,1H3,(H,19,20);1H
InChI key KWQWWUXRGIIBAS-UHFFFAOYSA-N
originator Abbott
Quality Level 100 
SMILES string Cl.COc1ccc(cc1)S(=O)(=O)Nc2cccnc2Nc3ccc(O)cc3
solubility DMSO: ≥15 mg/mL
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: ABT-751 is an orally bioavailable vascular disrupting agent (VDA) with a broad spectrum of antitumor activity. It binds to the colchicine binding site on β-tubulin and inhibits polymerization of microtubules.
Biochem/physiol Actions: ABT-751, a sulfonamide antimitotic agent, is under clinical trials to treat patients with various malignancies including refractory hematologic malignancies, non-small cell lung cancer (NSCLC), and colon cancer.
Biochem/physiol Actions: Orally bioavailable vascular disrupting agent (VDA) that binds to the colchicine binding site on β-tubulin and inhibits polymerization of microtubules; broad spectrum of antitumor activity.
Features and Benefits: This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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