Valsartan
SIGMA/SML0142 - ≥98% (HPLC)
Synonym: N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine
CAS Number: 137862-53-4
Empirical Formula (Hill Notation): C24H29N5O3
Molecular Weight: 435.52
MDL Number: MFCD00865840
Linear Formula: C24H29N5O3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to tan |
form | powder |
InChI | 1S/C24H29N5O3/c1-4-5-10-2 |
InChI key | ACWBQPMHZXGDFX-QFIPXVFZSA |
optical activity | [α]/D -55 to -70°, c = 1 in methanol |
originator | Novartis |
Quality Level | 100 ![]() |
SMILES string | CCCCC(=O)N(Cc1ccc(cc1)-c2 |
solubility | DMSO: ≥20 mg/mL |
storage condition | desiccated |
storage temp. | 2-8°C |
Application: | Mice were treated with valsartan to study the role of Ang II-dependent pathway in aldosterone-related effects. |
Biochem/physiol Actions: | Valsartan is an Angiotensin II type 1 (AT1) receptor antagonist and anti-hypertensive. Valsartan renders protection against heart attack and stroke resulting from abrupt increase in blood pressure. Valsartan reduces myocardial-infarction-rel |
Features and Benefits: | This compound is a featured product for ADME Tox research. Click here ![]() ![]() |
Features and Benefits: | This compound is featured on the Angiotensin Receptors ![]() ![]() |
Features and Benefits: | This compound was developed by Novartis ![]() ![]() |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() ![]() |
Signal word | Warning |
Hazard statements | H336 - H361d |
Precautionary statements | P201 - P308 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |