Drospirenone
SIGMA/SML0147 - ≥98% (HPLC)
Synonym: 6β,7β:15β,16β -
CAS Number: 67392-87-4
Empirical Formula (Hill Notation): C24H30O3
Molecular Weight: 366.49
EC Number: 266-679-2
MDL Number: MFCD00867350
Linear Formula: C24H30O3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to tan |
form | powder |
InChI | 1S/C24H30O3/c1-22-6-3-12( |
InChI key | METQSPRSQINEEU-HXCATZOESA |
optical activity | [α]/D -180 to -195°, c = 1 in methanol |
originator | Bayer |
Quality Level | 100 |
SMILES string | C[C@]12CCC(=O)C=C1[C@@H]3 |
solubility | DMSO: ≥15 |
storage condition | desiccated |
storage temp. | 2-8°C |
Application: | Drospirenone has been used as a progestogen agent in pond snail and fish. |
Application: | Drospirenone was tested for genotoxicity in rat and human hepatocytes. |
Biochem/physiol Actions: | Drospirenone is a fourth-generation progestin that has antimineralocorticoid, and antiandrogenic activity in addition to potent progestogenic activity. In two recent studies drospirenone appeared to double the risk of venous thromboembolism compared to levonorgestrel, although other studies found little added risk. |
Features and Benefits: | This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Features and Benefits: | This compound was developed by Bayer . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
Packaging: | 10, 50 mg in glass bottle |
Symbol | GHS08 |
Signal word | Danger |
Hazard statements | H360 |
Precautionary statements | P201 - P308 + P313 |
Hazard Codes | T |
Risk Statements | 60 |
Safety Statements | 36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 51111800 |