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Imidapril hydrochloride

SIGMA/SML0148 - ≥98% (HPLC)

Synonym: (4S)-3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride; Novaloc; TA 6366; Tanapril

CAS Number: 89396-94-1
Empirical Formula (Hill Notation): C20H27N3O6 · HCl
Molecular Weight: 441.91
MDL Number: MFCD00923828
Linear Formula: C20H27N3O6 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0148-10MG 10 mg
 $129.00
1/EA		 Add To Favorites
45-SML0148-50MG 50 mg
 $505.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to tan
form powder
InChI 1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1
InChI key LSLQGMMMRMDXHN-GEUPQXMHSA-N
optical activity [α]/D -50 to -70° in ethanol (c=0.5)
originator Trinity Pharma Solutions
Quality Level 100 
SMILES string Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2[C@@H](CN(C)C2=O)C(O)=O
solubility H2O: ≥5 mg/mL
storage temp. −20°C
Application: Imidapril hydrochloride may be used to test its effect on pharyngeal and laryngeal muscle to treat impaired swallowing.
Application: Imidapril hydrochloride was used as a standard in bioequivalence test by LC/MS method.
Biochem/physiol Actions: Imidapril hydrochloride is a long-acting inhibitor of angiotensin converting enzyme used in the treatment of hypertension, congestive heart failure and diabetic nephropathy. It restores decreased airway sensation and bladder sensation in patients with multiple sclerosis.
Biochem/physiol Actions: Imidapril is a potent angiotensin converting enzyme inhibitor and anti-hypertensive.
Features and Benefits: This compound is featured on the Angiotensin Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Trinity Pharma Solutions . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Imidapril comprises large acyl moiety and is hydrolyzed by carboxylesterase (CES) 1.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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