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CCT036477

SIGMA/SML0151 - ≥98% (HPLC)

Synonym: α-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine

CAS Number: 305372-78-5
Empirical Formula (Hill Notation): C21H18ClN3
Molecular Weight: 347.84
MDL Number: MFCD01831143
Linear Formula: C21H18ClN3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0151-5MG 5 mg
 $121.00
1/EA		 Add To Favorites
45-SML0151-25MG 25 mg
 $318.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to tan
form powder
InChI 1S/C21H18ClN3/c1-14-20(17-6-2-3-7-18(17)24-14)21(15-9-11-16(22)12-10-15)25-19-8-4-5-13-23-19/h2-13,21,24H,1H3,(H,23,25)
InChI key IFOHRIXRQPOHQZ-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cc1[nH]c2ccccc2c1C(Nc3ccccn3)c4ccc(Cl)cc4
solubility DMSO: ≥20 mg/mL (warm to 60°C)
storage temp. −20°C
Biochem/physiol Actions: CCT036477 is an inhibitor of Wnt signaling. It does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
Biochem/physiol Actions: Wnt β-catenin antagonist
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC); ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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