CCT036477

SIGMA/SML0151 - ≥98% (HPLC)

Synonym: α-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine

CAS Number: 305372-78-5
Empirical Formula (Hill Notation): C₂₁H₁₈ClN₃
Molecular Weight: 347.84
MDL Number: MFCD01831143
Linear Formula: C₂₁H₁₈ClN₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0151-5MG	5 mg	$138.00 1/EA		Add To Favorites
45-SML0151-25MG	25 mg	$428.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to tan
form	powder
InChI	1S/C21H18ClN3/c1-14-20(17-6-2-3-7-18(17)24-14)21(15-9-11-16(22)12-10-15)25-19-8-4-5-13-23-19/h2-13,21,24H,1H3,(H,23,25)
InChI key	IFOHRIXRQPOHQZ-UHFFFAOYSA-N
Quality Level	100
SMILES string	Cc1[nH]c2ccccc2c1C(Nc3ccccn3)c4ccc(Cl)cc4
solubility	DMSO: ≥20 mg/mL (warm to 60°C)
storage temp.	−20°C

Biochem/physiol Actions:	CCT036477 is an inhibitor of Wnt signaling. It does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC); ≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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