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Geniposide

SIGMA/SML0153 - ≥98% (HPLC)

Synonym: (1S,4αS,7αS)- 1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)- cyclopenta[c]pyran-4-carboxylic acid methyl ester

CAS Number: 24512-63-8
Empirical Formula (Hill Notation): C17H24O10
Molecular Weight: 388.37
MDL Number: MFCD16036219
Linear Formula: C17H24O10
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0153-10MG 10 mg
$234.00
1/EA
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45-SML0153-50MG 50 mg
$910.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C17H24O10/c1-24-15(23)9-6-25-16(11-7(4-18)2-3-8(9)11)27-17-14(22)13(21)12(20)10(5-19)26-17/h2,6,8,10-14,16-22H,3-5H2,1H3/t8-,10-,11-,12-,13+,14-,16+,17+/m1/s1
InChI key IBFYXTRXDNAPMM-BVTMAQQCSA-N
Quality Level 100 
shipped in wet ice
SMILES string COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1CC=C3CO
solubility H2O: ≥5 mg/mL
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation and upregulate downstream antioxidant protein HO-1 expression through the PI3K/Akt signaling pathway, which may account for its neuroprotective and antioxidative activity. Glucagon-like peptide 1 (GLP-1) receptor may also play a critical role in geniposide induced HO-1 expression.
Biochem/physiol Actions: Geniposide is an iridoid glycoside with antioxidative and other biological activities.
Packaging: 10, 50 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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