CJ-13610
SIGMA/SML0187 - ≥98% (HPLC)
Synonym: Tetrahydro-
CAS Number: 179420-17-8
Empirical Formula (Hill Notation): C22H23N3O2S
Molecular Weight: 393.50
MDL Number: MFCD00948114
Linear Formula: C22H23N3O2S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to tan |
form | powder |
InChI | 1S/C22H23N3O2S/c1-16-24-1 |
InChI key | VPTONMHDLLMOOV-UHFFFAOYSA |
originator | Pfizer |
Quality Level | 100 ![]() |
SMILES string | Cc1nccn1-c2ccc(Sc3cccc(c3 |
solubility | DMSO: ≥10 mg/mL |
storage condition | desiccated |
storage temp. | 2-8°C |
Application: | CJ-13610 may be used to study 5-lipoxygenase-mediated cell signaling. |
Biochem/physiol Actions: | CJ-13,610 is a potent inhbititor of 5-lipoxygenase (5-LO) activity (IC50 = 70 nM). |
Biochem/physiol Actions: | CJ-13610 inhibits the biosynthesis of leukotriene B4 and regulates the IL-6 mRNA expression in macrophages. It reduces fibrosis and necroinflammation of liver in carbon tetrachloride-treated mice. |
Features and Benefits: | This compound is featured on the Leukotriene Receptors ![]() ![]() |
Features and Benefits: | This compound was developed by Pfizer ![]() ![]() |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |