Fenoldopam mesylate

SIGMA/SML0198 - ≥98% (HPLC)

Synonym: Fenoldopam methanesulfonate

CAS Number: 67227-57-0
Empirical Formula (Hill Notation): C₁₆H₁₆ClNO₃ · CH₄O₃S
Molecular Weight: 401.86
EC Number: 266-612-7
MDL Number: MFCD04112986
Linear Formula: C₁₆H₁₆ClNO₃ · CH₄O₃S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0198-10MG	10 mg	$141.00 1/EA		Add To Favorites
45-SML0198-50MG	50 mg	$541.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to tan
form	powder
InChI	1S/C16H16ClNO3.CH4O3S/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;1-5(2,3)4/h1-4,7,13,18-21H,5-6,8H2;1H3,(H,2,3,4)
InChI key	CVKUMNRCIJMVAR-UHFFFAOYSA-N
mp	271 °C (lit.)
Quality Level	100
SMILES string	CS(O)(=O)=O.Oc1ccc(cc1)C2CNCCc3c(Cl)c(O)c(O)cc23
solubility	DMSO: ≥15 mg/mL at ~60 °C
storage condition	desiccated
storage temp.	room temp

Application:	Fenoldopam mesylate may be used to study dopamine D₁-mediated cell signaling.
Biochem/physiol Actions:	Dopamine D1-receptor agonist; Antihypertensive
Biochem/physiol Actions:	Fenoldopam mesylate (FM) is considered as an effective therapeutic agent to prevent the onset of postoperative AKI (PO-AKI). In healthy cats, FM can stimulate diuresis and be well-tolerated. This benzazepine-derivative is regional specific and does not cause cerebral vasodilation.
Biochem/physiol Actions:	Fenoldopam mesylate is a selective dopamine D₁ receptor agonist used as an antihypertensive agent. It is an agonist for D₁-like dopamine receptors and binds with moderate affinity to α2-adrenoceptors. It has no significant affinity for D₂-like receptors, α1 and α-adrenoceptors, 5HT₁ and 5HT₂ receptors, or muscarinic receptors. Fenoldopam mesylate causes peripheral vasodilation by stimulating dopamine-1receptors and α2-adrenoceptors, increasing renal blood flow.
Features and Benefits:	This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	10, 50 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H317 - H319
Precautionary statements	P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-36-42/43
Safety Statements	22-26-36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
mp	271 °C (lit.)
Storage Temp.	room temp
UNSPSC	12352200

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