Bropirimine
SIGMA/SML0218 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 56741-95-8
Empirical Formula (Hill Notation): C10H8BrN3O
Molecular Weight: 266.09
MDL Number: MFCD01689128
Linear Formula: C10H8BrN3O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C10H8BrN3O/c11-7-8(6-4 |
| InChI key | CIUUIPMOFZIWIZ-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | NC1=NC(=O)C(Br)=C(N1)c2cc |
| solubility | DMSO: ≥5 mg/mL (warm DMSO) |
| storage condition | desiccated |
| storage temp. | room temp |
| Application: | Bropirimine, an immunostimulating agent and toll like receptor (TLR7) agonist, is used in comparison with other TLR7 agonists such as imiquimod, R-848, loxoribine in interferon cell signaling research. Bropirimine may be used in experimental autoimmune encephalomyelitis (EAE) and bladder cancer research. |
| Biochem/physiol Actions: | Bropirimine is an immunostimulating agent. The compound induces production of α and β interferons and enhances NK cell function. Bropirimine has antiproliferative effects in cancer cell lines and tumor growth in in vivo models. |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P281 |
| Hazard Codes | Xn |
| Risk Statements | 63-62 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 51101500 |