TVP1022
SIGMA/SML0222 - ≥98% (HPLC)
Synonym: (1S)
CAS Number: 185517-74-2
Empirical Formula (Hill Notation): C12H13N
Molecular Weight: 171.24
MDL Number: MFCD09029306
Linear Formula: C12H13N
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C12H13N/c1-2-9-13-12-8 |
| InChI key | RUOKEQAAGRXIBM-LBPRGKRZSA |
| Quality Level | 100  |
| SMILES string | C#CCN[C@H]1CCc2ccccc12 |
| solubility | DMSO: ≥15 mg/mL |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | TVP1022, the S-isomer of rasagiline, an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. TVP1022, a neuroprotective and cytoprotective molecule, is also cardioprotective in rat models. Its activity is believed to involve stabilization of mitochondrial membrane potential, induction of Bcl-2 and activation of the PKC signalling pathway, enhancing the phosphorylation of protein kinase C and glycogen synthase kinase-3β. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H400 |
| Precautionary statements | P273 - P301 + P312 + P330 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50 |
| Safety Statements | 61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |