GW-803430
SIGMA/SML0230 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 515141-51-2
Empirical Formula (Hill Notation): C25H24ClN3O3S
Molecular Weight: 481.99
Linear Formula: C25H24ClN3O3S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C25H24ClN3O3S/c1-31-22 |
InChI key | MWULMTACIBZPGN-UHFFFAOYSA |
originator | GlaxoSmithKline |
Quality Level | 100 |
solubility | DMSO: ≥4 mg/mL at warmed to 60 °C |
storage temp. | 2-8°C |
Application: | GW-803430 may be used in MCHR1-mediated cell signaling studies. |
Biochem/physiol Actions: | GW-803430 antagonizes central MCHR1 and produces anxiolytic, anti-depressant and anti-obesity effects in rats and mice. It also controls the alcohol-seeking behavior in rats and is a promising treatment for alcohol use-related disorders. |
Biochem/physiol Actions: | GW-803430 is a centraly active and selective melanin-concentrating hormone receptor (MCHR) 1 antagonist |
Features and Benefits: | This compound is featured on the Melanin-Concentrating Hormone Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Features and Benefits: | This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 - H319 |
Precautionary statements | P301 + P312 + P330 - P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Statements | 22-36 |
Safety Statements | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 51111800 |