Synonym: (aS,3aR,7aS)-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt; KAD 1229; Mitiglinide hemicalcium salt; S 21403; [2(S)-cis]-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calclium salt
CAS Number: 145525-41-3
Empirical Formula (Hill Notation): C19H24NO3·0.5Ca
Molecular Weight: 334.44
MDL Number: MFCD09955408
Linear Formula: C19H24NO3·0.5Ca
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/2C19H25NO3.Ca/c2*21-18(20-12-15-8-4-5-9-16(15)13-20)11-17(19(22)23)10-14-6-2-1-3-7-14;/h2*1-3,6-7,15-17H,4-5,8-13H2,(H,22,23);/q;;+2/p-2/t2*15-,16+,17-;/m00./s1 |
| InChI key |
PMRVFZXOCRHXFE-FMEJWYFOSA-L |
| optical activity |
[α]/D +5 to +9° (c=1, MeOH) |
| Quality Level |
100  |
| SMILES string |
O=C(C[C@H](Cc1ccccc1)C(=O)O[Ca]OC(=O)[C@H](CC(=O)N2C[C@H]3CCCC[C@H]3C2)Cc4ccccc4)N5C[C@H]6CCCC[C@H]6C5 |
| solubility |
DMSO: ≥10 mg/mL at warmed to 60 °C |
| storage condition |
desiccated |
| storage temp. |
room temp |
| Biochem/physiol Actions: |
Mitiglinide calcium is a highly selective KATP channel antagonist |
| Biochem/physiol Actions: |
Mitiglinide is a drug for the treatment of type 2 diabetes. It is a highly selective KATP channel antagonist Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)–sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells. |
| Features and Benefits: |
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: |
10, 50 mg in glass bottle |
| Hazard statements |
H413 |
| Precautionary statements |
P273 - P501 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
