CDPPB

SIGMA/SML0235 - ≥98% (HPLC)

Synonym: 3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide

CAS Number: 781652-57-1
Empirical Formula (Hill Notation): C₂₃H₁₆N₄O
Molecular Weight: 364.40
Linear Formula: C₂₃H₁₆N₄O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0235-5MG	5 mg	$113.00 1/EA		Add To Favorites
45-SML0235-25MG	25 mg	$579.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C23H16N4O.H2O/c24-16-17-8-7-11-19(14-17)23(28)25-22-15-21(18-9-3-1-4-10-18)26-27(22)20-12-5-2-6-13-20;/h1-15H,(H,25,28);1H2
InChI key	GZHZEGYXLNXEBV-UHFFFAOYSA-N
Quality Level	100
SMILES string	O.O=C(Nc1cc(nn1-c2ccccc2)-c3ccccc3)c4cccc(c4)C#N
solubility	DMSO: ≥5 mg/mL at warmed to 60 °C
storage temp.	2-8°C

Application:	CDPPB may be used in mGluR5-mediated cell signaling studies.
Biochem/physiol Actions:	Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. This improves recognition memory and cognition deficits in schizophrenia.
Biochem/physiol Actions:	CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.
Features and Benefits:	This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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