Adefovir
SIGMA/SML0240 - ≥98% (HPLC)
Synonym: GS 0393; GS-393; P-
CAS Number: 106941-25-7
Empirical Formula (Hill Notation): C8H12N5O4P
Molecular Weight: 273.19
MDL Number: MFCD00866943
Linear Formula: C8H12N5O4P
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C8H12N5O4P/c9-7-6-8(11 |
InChI key | SUPKOOSCJHTBAH-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | Nc1ncnc2n(CCOCP(O)(O)=O)c |
solubility | 0.1 M NaOH: ≥5 mg/mL |
storage condition | desiccated |
storage temp. | −20°C |
Application: | Adefovir has been used to study its anti-retro viral effect on porcine endogenous retrovirus (PERV) activity. |
Biochem/physiol Actions: | Adefovir is an antiviral drug that after intracellular conversion to adefovir diphosphate inhibits hepatitis B virus (HBV) DNA polymerase (reverse transcriptase). |
Biochem/physiol Actions: | Adefovir, also known as 9-(2-phosphonylmethoxyeth |
Features and Benefits: | This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox ![]() ![]() ![]() |
Features and Benefits: | This compound is featured on the Adenylyl cyclases ![]() ![]() |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P301 + P310 |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |