ML169

SIGMA/SML0243 - ≥98% (HPLC)

Synonym: 2-[[1-[(5-Bromo-2-fluorophenyl)methyl]-1H-indol-3-yl]sulfonyl]-N-(5-methyl-3-isoxazolyl)-acetamide; VU0405652

CAS Number: 1222878-02-5
Empirical Formula (Hill Notation): C₂₁H₁₇BrFN₃O₄S
Molecular Weight: 506.34
MDL Number: MFCD23704785
Linear Formula: C₂₁H₁₇BrFN₃O₄S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0243-5MG	5 mg	$92.10 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C21H17BrFN3O4S/c1-13-8-20(25-30-13)24-21(27)12-31(28,29)19-11-26(18-5-3-2-4-16(18)19)10-14-9-15(22)6-7-17(14)23/h2-9,11H,10,12H2,1H3,(H,24,25,27)
InChI key	RUYRNYRGPSAXTK-UHFFFAOYSA-N
Quality Level	100
SMILES string	Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3cc(Br)ccc3F)c4ccccc24)no1
solubility	DMSO: >5 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	ML169 is a positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor M1 (CHRM1). ML169 does not cross react with other muscarinic receptors and is able to penetrate the blood brain barrier.
Biochem/physiol Actions:	ML169 is a positive allosteric modulator of muscarinic acetylcholine receptor M1.
Features and Benefits:	This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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