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Anisodamine

SIGMA/SML0252 - ≥98% (HPLC)

Synonym: α-(Hydroxymethyl)-benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; 6β-Hydroxyhyoscyamine; 6-Hydroxyhyoscyamine

CAS Number: 55869-99-3
Empirical Formula (Hill Notation): C17H23NO4
Molecular Weight: 305.37
Linear Formula: C17H23NO4
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0252-10MG 10 mg
$98.50
1/EA
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45-SML0252-50MG 50 mg
$382.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13-,14+,15+,16-/m0/s1
InChI key WTQYWNWRJNXDEG-RBZJEDDUSA-N
Quality Level 100 
SMILES string CN1[C@H]2C(O)C[C@@H]1C[C@H](OC(C(CO)C3=CC=CC=C3)=O)C2
solubility H2O: ≥5 mg/mL
storage temp. room temp
Biochem/physiol Actions: Anisodamine is a muscarinic receptor antagonist. Anisodamine is a naturally occurring atropine derivative isolated from Scopolia Tangutica Maxim plant indigenous to Tibet.
Biochem/physiol Actions: Anisodamine is a non‐specific cholinergic antagonist. It is considered less efficient and less toxic than atropine. Anisodamine interferes with liposome structure and affects cell membrane. It might act as an anti‐oxidant, in protecting against the damage caused by free radicals. Anisodamine is known to reduce cardiac conduction and also prevents arrhythmia. It can block thromboxane synthesis and might possess anti‐thrombotic function. Anisodamine has been useful in a number therapies including septic shock, circulatory disorders, organophosphorus poisoning, opiate addiction, snake bite and radiation damage. Disorders, such as migraine, gastric ulcers, rheumatoid arthritis, gastrointestinal colic, eclampsia, respiratory diseases, acute glomerular nephritis and obstructive jaundice can be treated with the help of anisodamine.
Features and Benefits: This compound is featured on the Acetylcholine Receptors (Muscarinic)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: Racemic mixture of diastereomers.
Packaging: 10, 50 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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