AEG 3482
SIGMA/SML0264 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 63735-71-7
Empirical Formula (Hill Notation): C10H8N4O2S2
Molecular Weight: 280.33
MDL Number: MFCD02064987
Linear Formula: C10H8N4O2S2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | faintly yellow to dark yellow |
form | powder |
InChI | 1S/C10H8N4O2S2/c11-18(15, |
InChI key | MQUYTXDAVCOCMX-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NS(=O)(=O)c1nn2cc(nc2s1)- |
solubility | DMSO: ≥15 mg/mL |
storage temp. | 2-8°C |
Biochem/physiol Actions: | AEG 3482 is an imidazothiadiazole sulfonamide of 281 D with an anti-apoptotic property. |
Biochem/physiol Actions: | AEG3284 is a compound that binds to heat shock protein 90 (HSP90), leading to heat shock factor 1 (HSF1) dependent expression of HSP70, an endogenous inhibitor of c-Jun N-terminal kinase (JNK) activity. Treatment of PC12 cells with AEF3284 blocks JNK dependent apoptosis. |
Features and Benefits: | This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |