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(2′Z)-Indirubin

SIGMA/SML0280 - ≥98% (HPLC)

Synonym: 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one; [Δ2,3′-Biindoline]-2′,3-dione (7CI,8CI); C.I. 73200; Couroupitine B; Indigo red; Indigopurpurin; NSC 105327

CAS Number: 906748-38-7
Empirical Formula (Hill Notation): C16H10N2O2
Molecular Weight: 262.26
MDL Number: MFCD00956441
Linear Formula: C16H10N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0280-5MG 5 mg
 $141.00
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45-SML0280-25MG 25 mg
 $557.00
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This image depicts SML0280-5MG.

 

assay ≥98% (HPLC)
form powder
InChI 1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13-
InChI key CRDNMYFJWFXOCH-YPKPFQOOSA-N
Quality Level 100 
SMILES string O=C1Nc2ccccc2C1=C3Nc4ccccc4C3=O
solubility DMSO: 2 mg/mL, clear (warmed)
storage condition protect from light
storage temp. 2-8°C
Biochem/physiol Actions: Indirubin is an inhibitor of GSK-3β and of cyclin-dependent kinases (CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p35). Also, indirubin is a specific Aryl Hydrocarbon receptor (AHR) ligand.
Biochem/physiol Actions: Indirubin is an inhibitor of GSK-3β and specific AHR ligand.
Features and Benefits: This compound is featured on the GSK-3  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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