Synonym: 3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one; [Δ2,3′-Biindoline]-2′,3-dione (7CI,8CI); C.I. 73200; Couroupitine B; Indigo red; Indigopurpurin; NSC 105327
CAS Number: 906748-38-7
Empirical Formula (Hill Notation): C16H10N2O2
Molecular Weight: 262.26
MDL Number: MFCD00956441
Linear Formula: C16H10N2O2
Product Type: Chemical
assay |
≥98% (HPLC) |
form |
powder |
InChI |
1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13- |
InChI key |
CRDNMYFJWFXOCH-YPKPFQOOSA-N |
Quality Level |
100 |
SMILES string |
O=C1Nc2ccccc2C1=C3Nc4ccccc4C3=O |
solubility |
DMSO: 2 mg/mL, clear (warmed) |
storage condition |
protect from light |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Indirubin is an inhibitor of GSK-3β and of cyclin-dependent kinases (CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p35). Also, indirubin is a specific Aryl Hydrocarbon receptor (AHR) ligand. |
Features and Benefits: |
This compound is featured on the GSK-3 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
Packaging: |
5, 25 mg in glass bottle |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |