Amorolfine hydrochloride

SIGMA/SML0283 - ≥98% (HPLC)

Synonym: (2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride; Ro 14-4767/002

CAS Number: 78613-38-4
Empirical Formula (Hill Notation): C₂₁H₃₅ON · HCl
Molecular Weight: 353.97
Linear Formula: C₂₁H₃₅ON · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0283-10MG	10 mg	$154.00 1/EA	Add To Favorites
45-SML0283-50MG	50 mg	$403.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+;
InChI key	XZKWIPVTHGWDCF-KUZYQSSXSA-N
Quality Level	100
SMILES string	Cl.CCC(C)(C)c1ccc(CC(C)CN2C[C@H](C)O[C@H](C)C2)cc1
solubility	DMSO: ≥5 mg/mL (warmed)
storage condition	desiccated
storage temp.	room temp

Application:	Amorolfine hydrochloride has been used as an antifungal agent.
Biochem/physiol Actions:	Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.
Biochem/physiol Actions:	Amorolfine hydrochloride is a potential for treating onychomycosis infected nails by topical application. A 5% solution combination with fluconazole is effective on sensitive fungus in fingernail onychomycosis.
Biochem/physiol Actions:	Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts.
Packaging:	10, 50 mg in glass bottle

Symbol	GHS07,GHS09
Signal word	Warning
Hazard statements	H302 - H315 - H411
Precautionary statements	P273 - P301 + P312 + P330 - P302 + P352
Hazard Codes	N
Risk Statements	22-38-50/53
Safety Statements	26-61
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

To Order From a Quote