Amorolfine hydrochloride
SIGMA/SML0283 - ≥98% (HPLC)
Synonym: (2R,6S)
CAS Number: 78613-38-4
Empirical Formula (Hill Notation): C21H35ON · HCl
Molecular Weight: 353.97
Linear Formula: C21H35ON · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C21H35NO.ClH/c1-7-21(5 |
InChI key | XZKWIPVTHGWDCF-KUZYQSSXSA |
Quality Level | 100 ![]() |
SMILES string | Cl.CCC(C)(C)c1ccc(CC(C)CN |
solubility | DMSO: ≥5 mg/mL (warmed) |
storage temp. | room temp |
Application: | Amorolfine hydrochloride has been used as an antifungal agent. |
Biochem/physiol Actions: | Amorolfine hydrochloride is a potential for treating onychomycosis infected nails by topical application. A 5% solution combination with fluconazole is effective on sensitive fungus in fingernail onychomycosis. |
Biochem/physiol Actions: | Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation. |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() ![]() |
Signal word | Warning |
Hazard statements | H302 - H315 - H411 |
Precautionary statements | P273 - P301 + P312 + P330 - P302 + P352 |
Hazard Codes | N |
Risk Statements | 22-38-50/53 |
Safety Statements | 26-61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | room temp |
UNSPSC | 12352200 |