Pleuromutilin

SIGMA/SML0285 - ≥95%

Synonym: Drosophilin B; Mutilin 14-glycolate; NSC 121145

CAS Number: 125-65-5
Empirical Formula (Hill Notation): C₂₂H₃₄O₅
Molecular Weight: 378.50
EC Number: 204-747-5
Linear Formula: C₂₂H₃₄O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0285-5MG	5 mg	$144.00 1/EA		Add To Favorites
45-SML0285-25MG	25 mg	$568.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
color	white to beige
form	powder
InChI	1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
InChI key	ZRZNJUXESFHSIO-BKUNHTPHSA-N
optical activity	[α]/D +30 to +40° (c=1; CH2Cl2)
Quality Level	100
shipped in	wet ice
SMILES string	C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CO
solubility	DMSO: >10 mg/mL (warmed)
storage temp.	−20°C

Biochem/physiol Actions:	Pleuromutilin is a diterpene that acts against gram positive bacteria and mycoplasm. It is present in Pleurotus mutilus and Pleurotus passecherianus. Pleuromutilin exhibits its antibacterial action by interfering with the prokaryotic 70S ribosomal subunit and inactivates initiation complex. Pleuromutilin is useful in treating mycoplasma infections in animals.
Biochem/physiol Actions:	Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	12352200

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