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Pleuromutilin

SIGMA/SML0285 - ≥95%

Synonym: Drosophilin B; Mutilin 14-glycolate; NSC 121145

CAS Number: 125-65-5
Empirical Formula (Hill Notation): C22H34O5
Molecular Weight: 378.50
EC Number: 204-747-5
Linear Formula: C22H34O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0285-5MG 5 mg
$148.00
1/EA
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45-SML0285-25MG 25 mg
$584.00
1/EA
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assay ≥95%
color white to beige
form powder
InChI 1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
InChI key ZRZNJUXESFHSIO-BKUNHTPHSA-N
optical activity [α]/D +30 to +40° (c=1; CH2Cl2)
Quality Level 100 
shipped in wet ice
SMILES string C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CO
solubility DMSO: >10 mg/mL (warmed)
storage temp. −20°C
Biochem/physiol Actions: Pleuromutilin is a diterpene that acts against gram positive bacteria and mycoplasm. It is present in Pleurotus mutilus and Pleurotus passecherianus. Pleuromutilin exhibits its antibacterial action by interfering with the prokaryotic 70S ribosomal subunit and inactivates initiation complex. Pleuromutilin is useful in treating mycoplasma infections in animals.
Biochem/physiol Actions: Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.
Biochem/physiol Actions: Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95%
Storage Temp. −20°C
UNSPSC 12352200

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