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Nepafenac

SIGMA/SML0288 - ≥98% (HPLC)

Synonym: 2-Amino-3-benzoyl-benzeneacetamide; AHR 9434; AL 6515

CAS Number: 78281-72-8
Empirical Formula (Hill Notation): C15H14N2O2
Molecular Weight: 254.28
MDL Number: MFCD08067732
Linear Formula: C15H14N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0288-10MG 10 mg
 $83.70
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45-SML0288-50MG 50 mg
 $325.00
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assay ≥98% (HPLC)
color faintly yellow to dark yellow
form powder
InChI 1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
InChI key QEFAQIPZVLVERP-UHFFFAOYSA-N
Quality Level 100 
SMILES string NC(=O)Cc1cccc(c1N)C(=O)c2ccccc2
solubility DMSO: ≥5 mg/mL
storage temp. room temp
Biochem/physiol Actions: Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.
Biochem/physiol Actions: Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) used in opthamology.
Biochem/physiol Actions: Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase.
Packaging: 10, 50 mg in glass bottle
Symbol GHS09  GHS09
Signal word Warning
Hazard statements H400
Precautionary statements P273
Hazard Codes N
Risk Statements 50/53
Safety Statements 60-61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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