Nepafenac

SIGMA/SML0288 - ≥98% (HPLC)

Synonym: 2-Amino-3-benzoyl-benzeneacetamide; AHR 9434; AL 6515

CAS Number: 78281-72-8
Empirical Formula (Hill Notation): C₁₅H₁₄N₂O₂
Molecular Weight: 254.28
MDL Number: MFCD08067732
Linear Formula: C₁₅H₁₄N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML0288-10MG	10 mg	$81.40 1/EA		Add To Favorites
45-SML0288-50MG	50 mg	$316.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	faintly yellow to dark yellow
form	powder
InChI	1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
InChI key	QEFAQIPZVLVERP-UHFFFAOYSA-N
Quality Level	100
SMILES string	NC(=O)Cc1cccc(c1N)C(=O)c2ccccc2
solubility	DMSO: ≥5 mg/mL
storage temp.	room temp

Biochem/physiol Actions:	Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.
Biochem/physiol Actions:	Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase.
Packaging:	10, 50 mg in glass bottle

Symbol	GHS09
Signal word	Warning
Hazard statements	H400
Precautionary statements	P273
Hazard Codes	N
Risk Statements	50/53
Safety Statements	60-61
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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