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Bromfenac sodium

SIGMA/SML0289 - ≥98% (HPLC)

Synonym: 2-Amino-3-(4-bromobenzoyl)benzeneacetic acid sodium salt

CAS Number: 91714-93-1
Empirical Formula (Hill Notation): C15H11BrNNaO3
Molecular Weight: 356.15
MDL Number: MFCD03701673
Linear Formula: C15H11BrNNaO3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0289-10MG 10 mg
$83.70
1/EA
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45-SML0289-50MG 50 mg
$342.00
1/EA
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assay ≥98% (HPLC)
color faintly yellow to dark yellow
form powder
InChI 1S/C15H12BrNO3.Na/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19;/h1-7H,8,17H2,(H,18,19);/q;+1/p-1
InChI key HZFGMQJYAFHESD-UHFFFAOYSA-M
Quality Level 100 
SMILES string [Na+].Nc1c(CC([O-])=O)cccc1C(=O)c2ccc(Br)cc2
solubility H2O: ≥5 mg/mL
storage condition desiccated
storage temp. 2-8°C
Application: Bromfenac sodium has been used:
• to study its ability to bind to melanin
• in the synthesis of bromfenac indolinone standard
• to analyze its permeability in porcine conjunctiva

Biochem/physiol Actions: Bromfenac exhibits antipyretic and prostaglandin synthetase inhibiting properties. It has therapeutic properties against the reduction of ocular pain and inflammation in postoperative cataract patients. Bromfenac acts as an effective agent against allergic conjunctivitis. It has the potential to treat acute muscle pain, osteoarthritis, and rheumatoid arthritis.
Biochem/physiol Actions: Bromfenac is a nonsteroidal anti inflammatory drug (NSAID) that inhibits both COX1 and COX2. It is used as an opthalmic analgesic.
Biochem/physiol Actions: Bromfenac is a nonsteroidal anti inflammatory drug (NSAID); COX1 and COX2 inhibitor; opthalmic analgesic.
Packaging: 10, 50 mg in glass bottle
Symbol GHS09  GHS09
Signal word Warning
Hazard statements H400
Precautionary statements P273
Hazard Codes N
Risk Statements 50
Safety Statements 61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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