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Telbivudine

SIGMA/SML0293 - ≥98% (HPLC)

Synonym: β-L-Thymidine; 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-Pyrimidinedione; 2′-Deoxy-L-thymidine; Epavudine; L-Thymidine; NV 02B; Sebivo

CAS Number: 3424-98-4
Empirical Formula (Hill Notation): C10H14N2O5
Molecular Weight: 242.23
MDL Number: MFCD02683612
Linear Formula: C10H14N2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0293-5MG 5 mg
 $134.00
1/EA		 Add To Favorites
45-SML0293-25MG 25 mg
 $538.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
InChI key IQFYYKKMVGJFEH-CSMHCCOUSA-N
optical activity [α]/D -15 to -22°, c = 1 in H2O
Quality Level 100 
SMILES string CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O
solubility H2O: 10 mg/mL (clear solution)
storage temp. 2-8°C
Application: Telbivudine has been used to explore the mechanisms of telbivudine (LdT) induced creatine kinase (CK) elevation.
Biochem/physiol Actions: Telbivudine is a nucleoside analog that is widely used to treat hepatitis B virus (HBV) infection.
Biochem/physiol Actions: Telbivudine is a synthetic molecule containing β-L-configuration. Telbivudine improves the estimated glomerular filtration rate (eGFR) in response to chronic hepatitis B (CHB). It prevents perinatal transmission and enhances the hepatitis B e antigen (HBeAg) seroconversion. It is also known to cause side effects such as creatine kinase (CK) elevation and fatal rhabdomyolysis.
Biochem/physiol Actions: Telbivudineis a Hepatitis B antiviral agent.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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