Tryptanthrin
SIGMA/SML0310 - ≥98% (HPLC)
Synonym: Couroupitine A; Indolo(2,1-
CAS Number: 13220-57-0
Empirical Formula (Hill Notation): C15H8N2O2
Molecular Weight: 248.24
MDL Number: MFCD00012073
Linear Formula: C15H8N2O2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | faintly yellow to dark yellow |
form | powder |
InChI | 1S/C15H8N2O2/c18-13-10-6- |
InChI key | VQQVWGVXDIPORV-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | O=C1C2=NC3=CC=CC=C3C(N2C4 |
solubility | DMSO: 2 mg/mL (warmed) |
storage condition | protect from light |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities. Tryptanthrin blocks leukotriene production in neutrophils and in whole blood assays, and in an in vivo rat pleurisy model. The compound also inhibits P-glycoprotein, and sensitizes resistant cancer cell lines to killing by cytotoxic agents. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |