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Tryptanthrin

SIGMA/SML0310 - ≥98% (HPLC)

Synonym: Couroupitine A; Indolo(2,1-b)quinazoline-6,12-dione; NSC 349447; Tryptanthrine

CAS Number: 13220-57-0
Empirical Formula (Hill Notation): C15H8N2O2
Molecular Weight: 248.24
MDL Number: MFCD00012073
Linear Formula: C15H8N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0310-5MG 5 mg
 $80.30
1/EA		 Add To Favorites
45-SML0310-25MG 25 mg
 $259.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color faintly yellow to dark yellow
form powder
InChI 1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H
InChI key VQQVWGVXDIPORV-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=C1C2=NC3=CC=CC=C3C(N2C4=C1C=CC=C4)=O
solubility DMSO: 2 mg/mL (warmed)
storage condition protect from light
storage temp. 2-8°C
Biochem/physiol Actions: Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities.
Biochem/physiol Actions: Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities. Tryptanthrin blocks leukotriene production in neutrophils and in whole blood assays, and in an in vivo rat pleurisy model. The compound also inhibits P-glycoprotein, and sensitizes resistant cancer cell lines to killing by cytotoxic agents.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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