Caramiphen hydrochloride
SIGMA/SML0319 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 125-85-9
Empirical Formula (Hill Notation): C18H27NO2 · HCl
Molecular Weight: 325.87
MDL Number: MFCD00242608
Linear Formula: C18H27NO2 · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C18H27NO2.ClH/c1-3-19( |
InChI key | MUPNXGNOIBYHSG-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | Cl.CCN(CC)CCOC(=O)C1(CCCC |
solubility | H2O: ≥5 mg/mL |
storage temp. | 2-8°C |
Application: | Caramiphen hydrochloride has been used to test its inhibitory effect on voltage-gated Na+ currents using the patch-clamp method. |
Biochem/physiol Actions: | Caramiphen hydrochloride is non-narcotic and possesses many biological functionalities of being antitussive, anticonvulsive, and neuroprotective. It induces sensory block and displays less toxicity when compared to bupivacaine. The local anesthetic functionality of caramiphen is mediated by its inhibitory effect on voltage-gated Na+ currents. |
Biochem/physiol Actions: | Caramiphen is an anti-muscarinic similar to atropine; muscarinic acetylcholine receptor antagonist. Caramiphen is commonly used as a cough suppresant, but is also administered for the treatment of Parkinson′s disease. The compound has also been shown to have anti-depressant properties that may involve inhibition of G protein-coupled inwardly rectifying potassium channel GIRK. |
Features and Benefits: | This compound is featured on the Acetylcholine Receptors (Muscarinic) ![]() ![]() |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |