FR180204
SIGMA/SML0320 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 865362-74-9
Empirical Formula (Hill Notation): C18H13N7
Molecular Weight: 327.34
MDL Number: MFCD14585805
Linear Formula: C18H13N7
Product Type: Chemical
assay | ≥98% (HPLC) |
color | faintly yellow to dark yellow |
form | powder |
InChI | 1S/C18H13N7/c19-17-12-10- |
InChI key | XVECMUKVOMUNLE-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | Nc1n[nH]c2nnc(cc12)-c3c(n |
solubility | DMSO: ≥10 mg/mL |
storage temp. | 2-8°C |
Application: | FR180204 has been used as ERK inhibitor: • to block extracellular-signal-regu • of extracellular-signal-regu • to determine if phosphorylation of this signaling protein is essential for mesenchymal stromal cell (MSC) derived therapeutic efficacy |
Biochem/physiol Actions: | FR180204 is a potent, cell-permeable, ATP-competitive inhibitor of ERK1 and ERK2 (mitogen-activated protein kinase (MAPK)/extracellular-sign |
Biochem/physiol Actions: | It can be used to study the roles of ERK as well as for drug development. |
Features and Benefits: | This compound is featured on the MAPKs ![]() ![]() |
Packaging: | 5, 25 mg in glass bottle |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |