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Cyamemazine

SIGMA/SML0321 - ≥98% (HPLC)

Synonym: 10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile; 7204 R. E.; 7204 RP; Ciamatil; Cianatil; Cyamemazin; R.P. 7204; TH 2602

CAS Number: 3546-03-0
Empirical Formula (Hill Notation): C19H21N3S
Molecular Weight: 323.46
EC Number: 222-594-2
MDL Number: MFCD00868180
Linear Formula: C19H21N3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0321-10MG 10 mg
 $159.00
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45-SML0321-50MG 50 mg
 $630.00
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assay ≥98% (HPLC)
color light yellow to yellow-green
form powder
InChI 1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
InChI key SLFGIOIONGJGRT-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC(CN(C)C)CN1c2ccccc2Sc3ccc(cc13)C#N
solubility DMSO: ≥5 mg/mL
storage temp. 2-8°C
Application: Cyamemazine has been used as an internal standard and antipsychotic drug to spike plasma samples in mass spectrometry studies. It has also been used as an analytical standard in gas chromatography-tandem mass spectroscopic (GC-MS/MS) analysis.
Biochem/physiol Actions: Cyamemazine belongs to the class of phenothiazine drugs. It is known to treat severe depression, schizophrenia and bipolar disorder.
Biochem/physiol Actions: Cyamemazine is a potent antagonist of 5-HT2C and 5-HT3 receptors with antipsychotic and anxiolytic properties.
Biochem/physiol Actions: Cyamemazine is a potent antagonist of 5-HT2C and 5-HT3 receptors.
Packaging: 10, 50 mg in glass bottle
Symbol GHS09  GHS09
Signal word Warning
Hazard statements H410
Precautionary statements P273 - P501
Hazard Codes Xi,N
Risk Statements 50
Safety Statements 61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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