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Hydroxy-Dynasore

SIGMA/SML0340 - ≥98% (HPLC)

Synonym: 3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide; 3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide

CAS Number: 1256493-34-1
Empirical Formula (Hill Notation): C18H14N2O5
Molecular Weight: 338.31
MDL Number: MFCD23704787
Linear Formula: C18H14N2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0340-5MG 5 mg
 $131.00
1/EA		 Add To Favorites
45-SML0340-25MG 25 mg
 $519.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color faintly yellow to dark yellow
form powder
InChI 1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
InChI key UAXHPUSKEWEOAP-DJKKODMXSA-N
Quality Level 100 
SMILES string Oc1cc(O)c(C=NNC(=O)c2cc3ccccc3cc2O)cc1O
solubility DMSO: >10 mg/mL
storage condition protect from light
storage temp. 2-8°C
Biochem/physiol Actions: Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.
Biochem/physiol Actions: Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor.
Other Notes: Air sensitive.
Packaging: 5, 25 mg in glass bottle
Hazard Codes N
Risk Statements 50
Safety Statements 61
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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