Alosetron hydrochloride
SIGMA/SML0346 - ≥98% (HPLC)
Synonym: 2,3,4,5-
CAS Number: 122852-69-1
Empirical Formula (Hill Notation): C17H18N4O·HCl
Molecular Weight: 330.81
MDL Number: MFCD09028027
Linear Formula: C17H18N4O·HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C17H18N4O.ClH/c1-11-13 |
InChI key | FNYQZOVOVDSGJH-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | CN1C2=C(C=CC=C2)C3=C1CCN( |
solubility | H2O: ≥5 mg/mL at warmed |
storage condition | desiccated |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pain, colonic transit and GI secretions that can contribute to the pathophysiology of irritable bowel syndrome (IBS). Alosetron is used clinically for treatment of women with severe diarrhea-predominant IBS. |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H301 - H319 - H412 |
Precautionary statements | P273 - P301 + P310 + P330 - P305 + P351 + P338 |
Hazard Codes | T,Xi |
Risk Statements | 25-36-52/53 |
Safety Statements | 26-45 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |