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TAK-715

SIGMA/SML0360 - ≥98% (HPLC)

Synonym: N-(4-(2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide

CAS Number: 303162-79-0
Empirical Formula (Hill Notation): C24H21N3OS
Molecular Weight: 399.51
MDL Number: MFCD17012805
Linear Formula: C24H21N3OS
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0360-5MG 5 mg
 $197.00
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assay ≥98% (HPLC)
color faintly yellow to dark yellow
form powder
InChI 1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)
InChI key HEKAIDKUDLCBRU-UHFFFAOYSA-N
Quality Level 100 
SMILES string CCc1nc(-c2cccc(C)c2)c(s1)-c3ccnc(NC(=O)c4ccccc4)c3
solubility DMSO: >15 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: TAK-715 is a dual p38 MAPK and CKId/e inhibitor; inhibitor of Wnt-3a-stimulated β-catenin signaling.
Biochem/physiol Actions: TAK-715 is a potent p38 inhibitor that also inhibits CKId/e (casein kinase Id/e), known activator of Wnt/β-catenin signaling.
Features and Benefits: This compound is featured on the MAPKs  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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