Synonym: 1,1-Bis(3-indolyl)-1-(p-t-butylphenyl)methane; 3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis-1H-indole
CAS Number: 94944-80-6
Empirical Formula (Hill Notation): C27H26N2
Molecular Weight: 378.51
EC Number: 305-658-5
MDL Number: MFCD18082348
Linear Formula: C27H26N2
Product Type: Chemical
| assay |
≥96% (HPLC) |
| color |
light orange to dark orange |
| form |
powder |
| InChI |
1S/C27H26N2/c1-27(2,3)19-14-12-18(13-15-19)26(22-16-28-24-10-6-4-8-20(22)24)23-17-29-25-11-7-5-9-21(23)25/h4-17,26,28-29H,1-3H3 |
| InChI key |
NCPVEZRBHNDCIV-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
CC(C)(C)c1ccc(cc1)C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 |
| solubility |
DMSO: >15 mg/mL |
| storage condition |
desiccated |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
DIM-C-pPhtBu, similar to other C-DIMs, exhibits a broad range of anticancer and antitumorigenic activities against multiple tumor types. DIM-C-pPhtBu causes apoptotic cell death of KB cells by activation of endoplasmic reticulum stress through induction of CHOP protein that is associated with the apoptosis in human oral cancer cells. Also it appears to induce an autophagic cell death in drug-resistant ER-negative breast tumors. |
| Packaging: |
5, 25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥96% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
