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Kartogenin

SIGMA/SML0370 - ≥98% (HPLC)

Synonym: 2-[(Biphenyl-4-yl)carbamoyl]benzoic acid; 4′-Phenyl-phthalanilic acid (8CI); KGN

CAS Number: 4727-31-5
Empirical Formula (Hill Notation): C20H15NO3
Molecular Weight: 317.34
MDL Number: MFCD00560510
Linear Formula: C20H15NO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0370-5MG 5 mg
 $110.00
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45-SML0370-25MG 25 mg
 $441.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
form powder
InChI 1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
InChI key SLUINPGXGFUMLL-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=C(NC1=CC=C(C2=CC=CC=C2)C=C1)C(C=CC=C3)=C3C(O)=O
solubility DMSO: >15 mg/mL
storage temp. room temp
Biochem/physiol Actions: Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparently, kartogenin induces chondrogenesis by regulating the nuclear localization of CBFβ.
Biochem/physiol Actions: Kartogenin is a small heterocyclic compound. It is involved in regulating runt-related transcription factor 1 (RUNX1), which plays an important role in chondrocyte proliferation and survival.
Packaging: 5, 25 mg in glass bottle
Hazard Codes Xn,N
Risk Statements 22-36-50/53
Safety Statements 60-61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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