MLR-1023
SIGMA/SML0371 - ≥98% (HPLC)
Synonym: 5-(3-Methylphenoxy)- 2(1H)-pyrimidinone; CP 26154; NSC 314335; Tolimidone
CAS Number: 41964-07-2
Empirical Formula (Hill Notation): C11H10N2O2
Molecular Weight: 202.21
MDL Number: MFCD00866900
Linear Formula: C11H10N2O2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C11H10N2O2/c1-8-3-2-4- |
| InChI key | HJQILFPVRNHTIG-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Cc1cccc(OC2=CNC(=O)N=C2)c |
| solubility | DMSO: 15 mg/mL (clear solution) |
| storage temp. | room temp |
| Biochem/physiol Actions: | MLR-1023 has a therapeutic potential to treat type 2 diabetes. |
| Biochem/physiol Actions: | MLR-1023 is a potent, orally active, allosteric activator of the non-receptor Src-related Lyn kinase that produces lasting glucose lowering, reduces HbA1c levels, and preserves pancreatic β-cells in db/db mice. MLR-1023 increased insulin receptor sensitivity. MLR-1023 (Tolimidone) is antiulcer agent. |
| Features and Benefits: | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |