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MLR-1023

SIGMA/SML0371 - ≥98% (HPLC)

Synonym: 5-(3-Methylphenoxy)- 2(1H)-pyrimidinone; CP 26154; NSC 314335; Tolimidone

CAS Number: 41964-07-2
Empirical Formula (Hill Notation): C11H10N2O2
Molecular Weight: 202.21
MDL Number: MFCD00866900
Linear Formula: C11H10N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0371-5MG 5 mg
 $101.00
1/EA		 Add To Favorites
45-SML0371-25MG 25 mg
 $391.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)
InChI key HJQILFPVRNHTIG-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cc1cccc(OC2=CNC(=O)N=C2)c1
solubility DMSO: 15 mg/mL (clear solution)
storage temp. room temp
Biochem/physiol Actions: MLR-1023 has a therapeutic potential to treat type 2 diabetes.
Biochem/physiol Actions: MLR-1023 is a potent, orally active, allosteric activator of the non-receptor Src-related Lyn kinase that produces lasting glucose lowering, reduces HbA1c levels, and preserves pancreatic β-cells in db/db mice. MLR-1023 increased insulin receptor sensitivity. MLR-1023 (Tolimidone) is antiulcer agent.
Biochem/physiol Actions: MLR-1023 is a potent, orally active, allosteric activator of the non-receptor Src-related Lyn kinase; insulin receptor-potentiating agent; antiulcer agent.
Features and Benefits: This compound is a featured product for Kinase Phosphatase Biology research. Click here  to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the InsR  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H319
Precautionary statements P305 + P351 + P338
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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