Nodinitib-1
SIGMA/SML0379 - ≥98% (HPLC)
Synonym: 1-
CAS Number: 799264-47-4
Empirical Formula (Hill Notation): C14H13N3O2S
Molecular Weight: 287.34
MDL Number: MFCD04322367
Linear Formula: C14H13N3O2S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C14H13N3O2S/c1-10-6-8- |
InChI key | SRFABRWQVPCPRG-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NC1=NC2=C(N1S(C3=CC=C(C)C |
solubility | DMSO: >10 mg/mL |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2. |
Packaging: | 5, 25 mg in glass bottle |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |