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SB-268262

SIGMA/SML0391 - ≥98% (HPLC)

Synonym: (+/-)-SB-273779; N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide

CAS Number: 217438-17-0
Empirical Formula (Hill Notation): C18H15N3O4S2
Molecular Weight: 401.46
MDL Number: MFCD10565932
Linear Formula: C18H15N3O4S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0391-5MG 5 mg
 $148.00
1/EA		 Add To Favorites
45-SML0391-25MG 25 mg
 $470.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C18H15N3O4S2/c1-12-5-3-4-6-14(12)20(2)17(22)13-7-8-16(15(11-13)21(23)24)27(25)18-19-9-10-26-18/h3-11H,1-2H3
InChI key YXHLPJQQPOMPGE-UHFFFAOYSA-N
Quality Level 100 
SMILES string CN(C(=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)c2nccs2)c3ccccc3C
solubility DMSO: >5 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor. SB-268262 inhibits CGRP binding, and CGRP-mediated stimulation of adenylyl cyclase activity in human neuroblastoma cells with IC50 values of 240 and 830 nM, respectively.
Features and Benefits: This compound is featured on the Calcitonin Gene-Related Peptides  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 41106305

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