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Tafenoquine succinate

SIGMA/SML0396 - ≥95% (HPLC)

Synonym: N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine; SB-252263; WR 238605

CAS Number: 106635-81-8
Empirical Formula (Hill Notation): C24H28F3N3O3 · C4H6O4
Molecular Weight: 581.58
MDL Number: MFCD00892249
Linear Formula: C24H28F3N3O3 · C4H6O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0396-10MG 10 mg
 $103.00
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45-SML0396-50MG 50 mg
 $419.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML0396-10MG.

 

assay ≥95% (HPLC)
color white to beige
form powder
InChI 1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8)
InChI key CQBKFGJRAOXYIP-UHFFFAOYSA-N
Quality Level 100 
SMILES string OC(=O)CCC(O)=O.COc1cc(C)c2c(Oc3cccc(c3)C(F)(F)F)c(OC)cc(NC(C)CCCN)c2n1
solubility DMSO: 5 mg/mL (clear solution)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Tafenoquine has been generally generated for oral administration and drug absorption increases when taken along with food. It is known to possess a longer half life.
Biochem/physiol Actions: Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.
Biochem/physiol Actions: Tafenoquine is an antimalarial.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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