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Tafenoquine succinate

SIGMA/SML0396 - ≥95% (HPLC)

Synonym: N-[2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine; SB-252263; WR 238605

CAS Number: 106635-81-8
Empirical Formula (Hill Notation): C24H28F3N3O3 · C4H6O4
Molecular Weight: 581.58
MDL Number: MFCD00892249
Linear Formula: C24H28F3N3O3 · C4H6O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0396-10MG 10 mg
 $93.40
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45-SML0396-50MG 50 mg
 $380.00
1/EA		 Add To Favorites

 

assay ≥95% (HPLC)
color white to beige
form powder
InChI 1S/C24H28F3N3O3.C4H6O4/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27;5-3(6)1-2-4(7)8/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3;1-2H2,(H,5,6)(H,7,8)
InChI key CQBKFGJRAOXYIP-UHFFFAOYSA-N
Quality Level 100 
SMILES string OC(=O)CCC(O)=O.COc1cc(C)c2c(Oc3cccc(c3)C(F)(F)F)c(OC)cc(NC(C)CCCN)c2n1
solubility DMSO: 5 mg/mL (clear solution)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Tafenoquine has been generally generated for oral administration and drug absorption increases when taken along with food. It is known to possess a longer half life.
Biochem/physiol Actions: Tafenoquine is an antimalarial primaquine analog being investigated to treat and prevent Plasmodium vivax infections. It can eliminate both blood and liver stages of Plasmodium vivax. Tafenoquine has also been tested as a therapy for leishmaniasis.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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