Salsolinol hydrobromide

SIGMA/SML0398 - ≥96% (HPLC)

Synonym: (R,S)-Salsolinol hydrobromide; 1,2,3,4-Tetrahydro-1-methylisoquinoline-6,7-diol hydrobromide; 1-Methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide; 1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline 1,2,3,4-Tetrahydro-1-methylisoquinoline-6,7-diol hydrobromide; 1-Methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrobromide

CAS Number: 59709-57-8
Empirical Formula (Hill Notation): C₁₀H₁₃NO₂ · HBr
Molecular Weight: 260.13
MDL Number: MFCD00012741
Linear Formula: C₁₀H₁₃NO₂ · HBr
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0398-10MG	10 mg	$120.00 1/EA	Add To Favorites
45-SML0398-50MG	50 mg	$474.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥96% (HPLC)
color	white to brown
form	powder
InChI	1S/C10H13NO2.BrH/c1-6-8-5-10(13)9(12)4-7(8)2-3-11-6;/h4-6,11-13H,2-3H2,1H3;1H
InChI key	OGMGXKJQIOUTTB-UHFFFAOYSA-N
Quality Level	100
SMILES string	Br.CC1NCCc2cc(O)c(O)cc12
solubility	H₂O: 5 mg/mL (warmed; clear solution)
storage condition	desiccated
storage temp.	2-8°C

Biochem/physiol Actions:	Salsolinol is the condensation product of acetaldehyde and dopamine. Salsolinol is a potential neurotoxin suspected to contribute to alcohol abuse.
Biochem/physiol Actions:	Salsolinol is the condensation product of acetaldehyde and dopamine. Salsolinol is a potential neurotoxin suspected to contribute to alcohol abuse. It appears that salsolinol excites the ventral tegmental area (VTA) dopamine neurons indirectly by activating μ-opioid receptors (MORs), which inhibit GABA neurons in the VTA.
Biochem/physiol Actions:	Salsolinol, a neurotoxin, can serve as a prolactin-releasing factor and an etiological factor in the tuberoinfundibular pathway and in Parkinson′s disease (PD), respectively. It can also act as a modulator of catecholaminergic neurotransmission in the nigrostriatal pathway. In central nervous system, salsolinol can change the role of dopaminergic neurons and dopamine metabolism.
Features and Benefits:	This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description:	Salsolinol (6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline) is present in various edibles. It is available as R and S enantiomers. R-salsolinol in predominantly found in the brain tissue of humans.
Packaging:	10, 50 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥96% (HPLC)
Storage Temp.	2-8°C
UNSPSC	51111800

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