BAY-X-1005
SIGMA/SML0411 - ≥98% (HPLC)
Synonym: α-Cyclopentyl-4-(2-quinolinylmethoxy)-(R)-benzeneacetic acid; (αR)-α-Cyclopentyl-4-(2-quinolinylmethoxy)-benzeneacetic acid; DG 031; Velifapon; Veliflapon
CAS Number: 128253-31-6
Empirical Formula (Hill Notation): C23H23NO3
Molecular Weight: 361.43
MDL Number: MFCD00870329
Linear Formula: C23H23NO3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C23H23NO3/c25-23(26)22 |
InChI key | ZEYYDOLCHFETHQ-JOCHJYFZSA |
Quality Level | 100 ![]() |
SMILES string | OC(=O)[C@H](C1CCCC1)c2ccc |
solubility | DMSO: 5 mg/mL (clear solution) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Bay-X-1005 is a potent inhibitor of 5-lipoxygenase activating protein (FLAP). Bay-X-1005 inhibits A23187-induced LTB4 production in human leucocytes with an IC50 value of 220 nM, and blocks IgE mediated airway contractions. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |