NCX 4040
SIGMA/SML0414 - ≥98% (HPLC)
Synonym: 2-(Acetyloxy)benzoic acid 4-
CAS Number: 287118-97-2
Empirical Formula (Hill Notation): C16H13NO7
Molecular Weight: 331.28
MDL Number: MFCD08062164
Linear Formula: C16H13NO7
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C16H13NO7/c1-11(18)23- |
InChI key | CTHNKWFUDCMLIQ-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | CC(=O)Oc1ccccc1C(=O)Oc2cc |
solubility | DMSO: 15 mg/mL (clear solution) |
storage condition | protect from light |
storage temp. | −20°C |
Biochem/physiol Actions: | NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines. |
Features and Benefits: | This compound is featured on the Nitric Oxide Synthases ![]() ![]() |
Packaging: | 5, 25 mg in glass bottle |
Symbol | ![]() ![]() ![]() |
Signal word | Danger |
Hazard statements | H317 - H318 - H400 |
Precautionary statements | P273 - P280 - P302 + P352 - P305 + P351 + P338 + P310 |
Hazard Codes | Xi |
Risk Statements | 41-43 |
Safety Statements | 26-36/37-39 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |