Synonym: 7-(Methylthio)-2-[(2,2-diphenylacetyl)amino]benzo[1,2-d:4,3-d′]bisthiazole
CAS Number: 397290-30-1
Empirical Formula (Hill Notation): C23H17N3OS3
Molecular Weight: 447.60
MDL Number: MFCD04419018
Linear Formula: C23H17N3OS3
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C23H17N3OS3/c1-28-23-25-17-13-12-16-19(20(17)30-23)29-22(24-16)26-21(27)18(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-13,18H,1H3,(H,24,26,27) |
InChI key |
UFOBDFMYJABXGK-UHFFFAOYSA-N |
Quality Level |
100 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
CSc1nc2ccc3nc(NC(=O)C(c4ccccc4)c5ccccc5)sc3c2s1 |
solubility |
DMSO: 5 mg/mL (clear solution; warmed) |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Gue1654 inhibits signaling of the chemoattractant GPCR 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-oxo-ETE) receptor (OXE-R), but only signaling involving Gβγ, not Gα signaling triggered upon activation of the Gαi-βγ heterotrimer by OXE-R. Gue1654 is the first small-molecule inhibitor for the oxoeicosanoid receptor and the first to uncouple Gα and Gβγ signaling within a heterotrimer for any GPCR. |
Packaging: |
5, 25 mg in glass bottle |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H302 |
Hazard Codes |
Xn |
Risk Statements |
22 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |