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BNS-22

SIGMA/SML0436 - ≥98% (HPLC)

Synonym: 8-[(3,4-Dihydro-2H-quinolin-1-yl)carbonyl]-5,7-dimethoxy-4-propyl-2H-chromen-2-one

CAS Number: 1151668-24-4
Empirical Formula (Hill Notation): C24H25NO5
Molecular Weight: 407.46
MDL Number: MFCD22628799
Linear Formula: C24H25NO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0436-5MG 5 mg
 $121.00
1/EA		 Add To Favorites
45-SML0436-25MG 25 mg
 $321.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C24H25NO5/c1-4-8-16-13-20(26)30-23-21(16)18(28-2)14-19(29-3)22(23)24(27)25-12-7-10-15-9-5-6-11-17(15)25/h5-6,9,11,13-14H,4,7-8,10,12H2,1-3H3
InChI key LRPUQCTZOSTSGL-UHFFFAOYSA-N
Quality Level 100 
SMILES string COC1=C2C(OC(C=C2CCC)=O)=C(C(N3C(C=CC=C4)=C4CCC3)=O)C(OC)=C1
solubility DMSO: 2 mg/mL (clear solution; warmed)
storage temp. 2-8°C
Biochem/physiol Actions: BNS-22 is a derivative of natural product GUT-70 isolated from the stem bark of Calophyllum brasiliense exhibits antiproliferative activity against human cancer cells. It appears that BNS-22 is a specific DNA-topoisomerase II (TOPO2) catalytic inhibitor. BNS-22 does not induce DNA damage.
Biochem/physiol Actions: BNS-22 is a DNA-topoisomerase II (TOPO2) catalytic inhibitor.
Packaging: 5, 25 mg in glass bottle
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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